it kind of depends on the car design.
I had an 08 Z51 that had the goodyear F1 supercars did not really suffer much of an issue. on my Z06 with the wide rear fenders it is the front kicker rocks at the rear quarters. So on it to solve the issue you eather clear bra the rear quarte area by the brake ducts, run apis front fender flares.
The sucky thing about his is getting somone do design a product that does not may the car look stupid.
2013 ZL1 (president of the tangent oregon trophy husband association, founding and only member)
2013 Megacab 8" lift 38"mt's