I have used Torco Accelerator for many years.. We recommend using it on everyone of our high boost applications as a mixture with 93 (Plus the methanol) when you know you are going out to purposely beat the snot out of the car!
As per tuning the high boost V6s, just like any other application if you are getting REAL knock retard you need to reduce timing. If you are getting false knock you can de-sensitize the sensors some to account for it. If you run 93 octane, at your boost level you should be fine without having to add Torco, just reduce timing as I said IF its true knock. However, this is hard when doing mail order because you are relying on the other party to listen for this knock that you are accustomed to hearing.