I have been there many times and it is always fun.
The best time to go is the middle of the week on non holiday weeks. Less traffic and cops.
Usually make a run through at a leisurely pace, then make a return run when you are fairly sure it's safe. Most of the time if the road is busy people will flash their lights to warn you of cops or other dangerous situations ahead, but you have to be very careful anyway. Many people think they are better drivers than they really are and get in over their heads and end up crossing into the other lane on blind curves. Always be prepared for that.
I have had a few close calls with drivers like that, and if have seen several accidents where people have run off the road.